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Beta-Amyloid (1-42) (bs-0107P)
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說明書: 100ug  500ug  1mg
100ug/890.00元
500ug/2680.00元
1mg/3800.00元
大包裝/詢價
產品編號 bs-0107P
英文名稱 Beta-Amyloid (1-42) Peptide
中文名稱 β淀粉樣肽(1-42) 多肽
別    名 Aβ 1-42; Amyloid Beta (1-42).  
Specific References  (0)     |     bs-0107P has been referenced in 0 publications.
分 子 量 4.514kDa
性    狀 Lyophilized or Liquid
多肽活性 活性多肽
序    列 DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA
產品來源 合成
分    類
偶聯蛋白
純化方法 HPLC
產品應用 Biological activity 
Immunology research 
Blocking Peptide of The bs-0107R Antibody
保存條件 Store at -20 °C for one year. The lyophilized powder is stable at room temperature for at least one month and for greater than a year when kept at -20°C. Upon reconstituted, aliquot and store at -20°C or -80°C. Avoid repeated freeze/thaw cycles.
產品介紹 Amyloid beta (Aβ or Abeta) denotes peptides of 36–43 amino acids that are crucially involved in Alzheimer's disease as the main component of the amyloid plaques found in the brains of Alzheimer patients. The peptides derive from the amyloid precursor protein (APP), which is cleaved by beta secretase and gamma secretase to yield Aβ. Aβ molecules can aggregate to form flexible soluble oligomers which may exist in several forms. It is now believed that certain misfolded oligomers (known as "seeds") can induce other Aβ molecules to also take the misfolded oligomeric form, leading to a chain reaction akin to a prion infection. The oligomers are toxic to nerve cells. The other protein implicated in Alzheimer's disease, tau protein, also forms such prion-like misfolded oligomers, and there is some evidence that misfolded Aβ can induce tau to misfold.




β-淀粉樣蛋白來自β-淀粉樣蛋白原,在腦組織的細胞外呈絲狀蛋白樣沉積 ,是淀粉樣結節性神經炎病變的主要蛋白成分,在神經纖維中也有沉積。
在老年性癡呆Alzheimer病中,大腦皮質中特征性地出現β-淀粉樣蛋白沉積形成的老年斑。

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